Immunofluorescence microscopy is one cell biology's most useful and profoundly important tools, but present immunofluorescence methods remain severely limited, especially as applied to imaging dense and complex molecular architectures such as the brain's. The Smith lab is developing new immunofluorescence methods that provide breakthrough capabilities to resolve single synapses, arbors and networks within intact brain tissues. Here, dendrites and synapses are visualized in mouse cerebral cortex. Learn more about Array Tomography at the Stanford Array Tomography Resource (SATR) website.
